7-(Diethylamino)-4-methyl-2H-chromen-2-one

Modify Date: 2024-01-02 16:47:25

7-(Diethylamino)-4-methyl-2H-chromen-2-one structure	Common Name	7-(Diethylamino)-4-methyl-2H-chromen-2-one
	CAS Number	91-44-1	Molecular Weight	231.290
	Density	1.1±0.1 g/cm3	Boiling Point	391.7±37.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₇NO₂	Melting Point	72-75 °C
	MSDS	Chinese USA	Flash Point	152.0±17.4 °C

Use of 7-(Diethylamino)-4-methyl-2H-chromen-2-one

7-Diethylamino-4-methylcoumarin is a laser dye[1].

Name	coumarin 460
Synonym	More Synonyms

Description	7-Diethylamino-4-methylcoumarin is a laser dye[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Yip R W, et al. Photophysics of 7-diethylamino-4-methylcoumarin: picosecond time-resolved absorption and amplified emission study. Journal of Photochemistry and Photobiology A: Chemistry, 1990, 54(2): 263-270.

Density	1.1±0.1 g/cm3
Boiling Point	391.7±37.0 °C at 760 mmHg
Melting Point	72-75 °C
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.290
Flash Point	152.0±17.4 °C
Exact Mass	231.125931
PSA	33.45000
LogP	4.15
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.574
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	slightly soluble

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN6370000

CHEMICAL NAME :: Coumarin, 7-diethylamino-4-methyl-

CAS REGISTRY NUMBER :: 91-44-1

BEILSTEIN REFERENCE NO. :: 0193303

LAST UPDATED :: 199803

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C14-H17-N-O2

MOLECULAR WEIGHT :: 231.32

WISWESSER LINE NOTATION :: T66 BOVJ E1 IN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1780 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: SRTCAC Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. (Tohoku University, Research Institute for Tuberculosis and Cancer, 4-1 Seiryo-machi, Sendai, Japan) V.1- 1949- Volume(issue)/page/year: 36(1-4),10,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03230 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9410 No. of Facilities: 1470 (estimated) No. of Industries: 11 No. of Occupations: 18 No. of Employees: 21642 (estimated) No. of Female Employees: 8996 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21;R36/37/38
Safety Phrases	S37/39-S26
RIDADR	NONH for all modes of transport
RTECS	GN6370000
HS Code	2932209090

Precursor 10
CAS#:141-97-9 Ethyl acetoacetate CAS#:91-68-9 3-(diethylamino... CAS#:120-72-9 Indole CAS#:107995-74-4 3-iodo-4-methyl...
CAS#:288-32-4 Imidazole CAS#:51-17-2 Benzimidazole CAS#:188290-36-0 Thiophene(SIV) CAS#:292638-84-7 phenylene-ethylene
CAS#:110-86-1 Pyridine CAS#:96-54-8 1-Methylpyrrole
DownStream 10
CAS#:107743-39-5 7-diethylamino-... CAS#:26093-31-2 7-Amino-4-methy... CAS#:28821-18-3 7-(ETHYLAMINO)-... CAS#:71173-56-3 7-(ethylamino)-...
CAS#:121983-26-4 1-endo-cyano-8b... CAS#:121983-25-3 1-endo-butoxy-8... CAS#:118116-72-6 3-nitro-4-methy... CAS#:54711-38-5 7-(Diethylamino...
CAS#:137832-22-5 7-[ethyl(1-hydr... CAS#:132220-02-1 7-(diethylamino...

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Characterization of mixtures of compounds produced in chlorpromazine aqueous solutions by ultraviolet laser irradiation: their applications in antimicrobial assays.

J. Biomed. Opt. 20 , 051002, (2014)

The study reports an investigation of the photoproducts obtained by exposure of chlorpromazine hydrochloride in ultrapure water (concentration 2 mg/mL) to a 266-nm laser beam obtained by fourth harmon...

Near infrared light responsive hybrid nanoparticles for synergistic therapy.

Biomaterials 100 , 76-90, (2016)

A near infrared (NIR) light responsive chromophore 7-(diethylamino)-4-(hydroxymethyl)-2H-chromen-2-one (DEACM) was synthesized and incorporated to β-cyclodextrins with cRGD functionalized poly(ethylen...

Identification of faceseal leak sites on a half-mask respirator.

Am. Ind. Hyg. Assoc. J. 51(5) , 280-4, (1990)

A method has been developed to identify the location and shape of respirator faceseal leak sites by the deposition of a fluorescent tracer. An aerosol generation, conditioning, and exposure system to ...

COUMARIN 1

UVITEX WGS

aclarat8678

Coumalux

c47

7d4mc

COUMARIN I

7-NEt2-4-CH3-coumarin

7-Diethylamino-4-methylcoumarin

Coumarin 460

2H-1-Benzopyran-2-one, 7- (diethylamino)-4-methyl-

T66 BOVJ E1 IN2&2

7-(Diethylamino)-4-methyl-2H-chromen-2-one

Coumarin, 7-(diethylamino)-4-methyl-

2H-1-Benzopyran-2-one, 7-(diethylamino)-4-methyl-

MFCD00006864

hakkolp

EINECS 202-068-9

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 7-(Diethylamino)-4-methyl-2H-chromen-2-one
Price: ￥108.0/25g ￥318.0/100g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fluorescent Brightener 52
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 7-Diethylamino-4-methylcoumarin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM CAS:91-44-1 7-Diethylamino-4-methylcoumarin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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