α-Helical CRF(9-41)

Modify Date: 2024-01-04 17:58:53

α-Helical CRF(9-41) structure	Common Name	α-Helical CRF(9-41)
	CAS Number	90880-23-2	Molecular Weight	3826.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆₆H₂₇₄N₄₆O₅₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of α-Helical CRF(9-41)

α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2].

Name	α-Helical CRF(9-41)

Description	α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CRFR Research Areas >> Neurological Disease
Target	KB: ~100 nM (CRF2 receptor)[2] EC50: 140 nM (CRF1 receptor)[2]
References	[1]. Sonia Tucci, et al. Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl). 2003 May;167(3):251-6. [2]. Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35.

Molecular Formula	C₁₆₆H₂₇₄N₄₆O₅₃S₂
Molecular Weight	3826.40

DC Chemicals Limited
China
Product Name: α-Helical CRF(9-41)
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CORTICOTROPIN RELEASING FACTOR ANTAGONIST
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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α-Helical CRF(9-41)

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