5,7-Dimethoxyluteolin

Modify Date: 2024-01-02 15:28:29

5,7-Dimethoxyluteolin Structure
5,7-Dimethoxyluteolin structure
Common Name 5,7-Dimethoxyluteolin
CAS Number 90363-40-9 Molecular Weight 314.28900
Density N/A Boiling Point N/A
Molecular Formula C17H14O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5,7-Dimethoxyluteolin


5,7-Dimethoxyluteolin, a 5,7-dimethylluteolin derivative, is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM[1].

 Names

Name 2-(3,4-dihydroxyphenyl)-5,7-dimethoxychromen-4-one
Synonym More Synonyms

 5,7-Dimethoxyluteolin Biological Activity

Description 5,7-Dimethoxyluteolin, a 5,7-dimethylluteolin derivative, is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM[1].
Related Catalog
Target

EC50: 3.417μM (Dopamine transporter) [1]

References

[1]. Jiange Zhang, et al. Discovery and synthesis of novel luteolin derivatives as DAT agonists. Bioorg Med Chem. 2010 Nov 15;18(22):7842-8.

 Chemical & Physical Properties

Molecular Formula C17H14O6
Molecular Weight 314.28900
Exact Mass 314.07900
PSA 89.13000
LogP 2.88840

 Synthetic Route

~25%

5,7-Dimethoxyluteolin Structure

5,7-Dimethoxylu...

CAS#:90363-40-9

Literature: Zhang, Jiange; Liu, Xianbo; Lei, Xinsheng; Wang, Lei; Guo, Lihe; Zhao, Gang; Lin, Guoqiang Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 22 p. 7842 - 7848

~12%

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

~9%

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

 Synonyms

Luteolin-5,7-dimethylether
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dimethoxy
2-(3,4-dihydroxyphenyl)-5,7-dimethoxy-4H-chromen-4-one