LDH-IN-2

Modify Date: 2024-04-06 21:04:55

LDH-IN-2 Structure
LDH-IN-2 structure
Common Name LDH-IN-2
CAS Number 893739-96-3 Molecular Weight 204.18
Density N/A Boiling Point N/A
Molecular Formula C11H8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LDH-IN-2


LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1)[1].

 Names

Name LDH-IN-2

 LDH-IN-2 Biological Activity

Description LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1)[1].
Related Catalog
In Vitro LDH-IN-2L (compound 34) (10 μM; 24 h) 在 Agxt1-/- 小鼠原代肝细胞中抑制草酸产生的抑制率为 89%[1]。
References

[1]. Moya-Garzón MD, et al. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1. J Med Chem. 2018 Aug 23;61(16):7144-7167.  

 Chemical & Physical Properties

Molecular Formula C11H8O4
Molecular Weight 204.18