Imidapril

Modify Date: 2024-01-13 20:22:12

Imidapril structure	Common Name	Imidapril
	CAS Number	89371-37-9	Molecular Weight	405.44500
	Density	1.266 g/cm3	Boiling Point	577ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₇N₃O₆	Melting Point	195-197°C
	MSDS	N/A	Flash Point	302.8ºC

Use of Imidapril

Imidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2].

Name	(4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
Synonym	More Synonyms

Description	Imidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-9
References	[1]. Robinson DM, et al. Imidapril: a review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure. Drugs. 2007;67(9):1359-78. [2]. Yamamoto D, et al. Molecular mechanism of imidapril for cardiovascular protection via inhibition of MMP-9. J Mol Cell Cardiol. 2007 Dec;43(6):670-6.

Density	1.266 g/cm3
Boiling Point	577ºC at 760 mmHg
Melting Point	195-197°C
Molecular Formula	C₂₀H₂₇N₃O₆
Molecular Weight	405.44500
Flash Point	302.8ºC
Exact Mass	405.19000
PSA	116.25000
LogP	1.14290
Storage condition	-20°C Freezer

Risk Phrases	R22:Harmful if swallowed. R34:Causes burns.
Safety Phrases	S26-S36/37/39
RIDADR	1759
Packaging Group	II
Hazard Class	8

N/A

CAS#:89371-36-8

~94%

Imidapril

CAS#:89371-37-9

Literature: US4508727 A1, ; US 4508727 A

N/A

CAS#:117605-23-9

Imidapril

CAS#:89371-37-9

Literature: Chemical and Pharmaceutical Bulletin, , vol. 39, # 6 p. 1374 - 1377

Precursor 0
DownStream 2
CAS#:64-17-5 Ethanol CAS#:89371-44-8 Imidaprilate

imidapril

(4S)-3-<(2S)-2-<N-<(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl>amino>propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylic Acid

Hipertene (TN)

Imidapril [BAN:INN]

Imidaprilum

(S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid

Imidapril HCl

(4S)-1-methyl-3-{(2S)-2-[N-(1S)-1-ethoxycarbonyl-3-phenylpropyl)amino]propionyl}-2-oxoimidazolidine-4-carboxylic acid

Imidapril (INN)

Imidaprilum [INN-Latin]

MFCD00870777

Zhejiang Hangyu API Co., Ltd
China
Product Name: Imidapril
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Get all suppliers and price by the below link:

Imidapril suppliers

Imidapril price

Imidapril

Use of Imidapril

Names

Imidapril Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms