m-PEG8-Amine

Modify Date: 2024-01-04 10:54:19

m-PEG8-Amine Structure
m-PEG8-Amine structure
Common Name m-PEG8-Amine
CAS Number 869718-81-0 Molecular Weight 383.47800
Density 1.054 Boiling Point 448ºC at 760 mmHg
Molecular Formula C17H37NO8 Melting Point N/A
MSDS N/A Flash Point 213.9ºC

 Use of m-PEG8-Amine


m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonym More Synonyms

 m-PEG8-Amine Biological Activity

Description m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Joshua D. Thoma, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.

 Chemical & Physical Properties

Density 1.054
Boiling Point 448ºC at 760 mmHg
Molecular Formula C17H37NO8
Molecular Weight 383.47800
Flash Point 213.9ºC
Exact Mass 383.25200
PSA 99.86000
LogP 0.40800
Storage condition -20 °C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~92%

m-PEG8-Amine Structure

m-PEG8-Amine

CAS#:869718-81-0

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ;

~90%

m-PEG8-Amine Structure

m-PEG8-Amine

CAS#:869718-81-0

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

3,6,9,12,15,18,21,24-OCTAOXAPENTACOSAN-1-AMINE
AmbotzPEG1700
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