m-PEG8-azide

Modify Date: 2024-04-08 08:22:31

m-PEG8-azide Structure
m-PEG8-azide structure
Common Name m-PEG8-azide
CAS Number 869718-80-9 Molecular Weight 409.47500
Density N/A Boiling Point N/A
Molecular Formula C17H35N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-azide


m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 25-azido-2,5,8,11,14,17,20,23-octaoxapentacosane
Synonym More Synonyms

 m-PEG8-azide Biological Activity

Description m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

 Chemical & Physical Properties

Molecular Formula C17H35N3O8
Molecular Weight 409.47500
Exact Mass 409.24200
PSA 123.59000
LogP 0.51206
Index of Refraction 1.46

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

MFCD13184962