m-PEG8-azide

Names

[ CAS No. ]:
869718-80-9

[ Name ]:
m-PEG8-azide

[Synonym ]:
MFCD13184962

Biological Activity

[Description]:

m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₃₅N₃O₈

[ Molecular Weight ]:
409.47500

[ Exact Mass ]:
409.24200

[ PSA ]:
123.59000

[ LogP ]:
0.51206

[ Index of Refraction ]:
1.46

m-PEG8-azide

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds