Litoxetine

Modify Date: 2024-01-21 11:27:55

Litoxetine Structure
Litoxetine structure
Common Name Litoxetine
CAS Number 86811-09-8 Molecular Weight 241.32800
Density 1.1g/cm3 Boiling Point 387.1ºC at 760 mmHg
Molecular Formula C16H19NO Melting Point N/A
MSDS N/A Flash Point 159.2ºC

 Use of Litoxetine


Litoxetine (SL 81.0385) is a selective 5-HT uptake inhibitor. Litoxetine is a 5-HT3 receptor antagonist with a Ki of 85 nM for cerebral 5-HT3 receptors. Litoxetine is an antidepressant and has antiemetic properties[1].

 Names

Name 4-(naphthalen-2-ylmethoxy)piperidine
Synonym More Synonyms

 Litoxetine Biological Activity

Description Litoxetine (SL 81.0385) is a selective 5-HT uptake inhibitor. Litoxetine is a 5-HT3 receptor antagonist with a Ki of 85 nM for cerebral 5-HT3 receptors. Litoxetine is an antidepressant and has antiemetic properties[1].
Related Catalog
References

[1]. I Angel, et al. Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties. Eur J Pharmacol. 1993 Mar 2;232(2-3):139-45.  

 Chemical & Physical Properties

Density 1.1g/cm3
Boiling Point 387.1ºC at 760 mmHg
Molecular Formula C16H19NO
Molecular Weight 241.32800
Flash Point 159.2ºC
Exact Mass 241.14700
PSA 21.26000
LogP 3.43720
Index of Refraction 1.607

 Synonyms

Litoxetinum [INN-Latin]
Litoxetina
Litoxetine
Litoxetinum
Litoxetina [INN-Spanish]
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