EACC
Modify Date: 2025-09-18 08:20:43
EACC structure
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Common Name | EACC | ||
|---|---|---|---|---|
| CAS Number | 864941-31-1 | Molecular Weight | 369.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H11N3O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EACCEACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1]. |
| Name | EACC |
|---|
| Description | EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1]. |
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| Related Catalog | |
| Target |
Autophagy[1] |
| In Vitro | EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function[1]. EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes[1]. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17[1]. |
| References |
| Molecular Formula | C13H11N3O6S2 |
|---|---|
| Molecular Weight | 369.37 |
| InChIKey | ISLJZDYAPAUORR-UHFFFAOYSA-N |
| SMILES | CCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccc([N+](=O)[O-])s1 |
| Hazard Codes | Xi |
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