864941-31-1
864941-31-1 structure
- Name: EACC
- Chemical Name: EACC
- CAS Number: 864941-31-1
- Molecular Formula: C13H11N3O6S2
- Molecular Weight: 369.37
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2019-10-07 22:02:52
- Modify Date: 2024-02-07 15:59:44
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EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1].
| Name | EACC |
|---|
| Description | EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1]. |
|---|---|
| Related Catalog | |
| Target |
Autophagy[1] |
| In Vitro | EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function[1]. EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes[1]. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17[1]. |
| References |
| Molecular Formula | C13H11N3O6S2 |
|---|---|
| Molecular Weight | 369.37 |
| Hazard Codes | Xi |
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