PTP1B-IN-22

Modify Date: 2024-04-11 21:55:17

PTP1B-IN-22 structure	Common Name	PTP1B-IN-22
	CAS Number	86109-60-6	Molecular Weight	344.41
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₂N₂O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PTP1B-IN-22

PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has PTP1B inhibition and glucose uptake in skeletal muscle L6 myotubes[1].

Name	WYE-176244
Synonym	More Synonyms

Description	PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has PTP1B inhibition and glucose uptake in skeletal muscle L6 myotubes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
In Vitro	PTP1B-IN-22 (compound 3j; 骨骼肌 L6 肌管) 表现出 66.4% 的体外 PTP1B 抑制和 39.6% 的葡萄糖摄取增加[1]。
References	[1]. Prashant J, et, al. Molecular modeling and synthesis of ZINC02765569 derivatives as protein tyrosine phosphatase 1B inhibitors: lead optimization study. 2012;22: 1618-23.

Density	1.5±0.1 g/cm3
Molecular Formula	C₁₆H₁₂N₂O₃S₂
Molecular Weight	344.41
Exact Mass	344.028931
LogP	4.33
Index of Refraction	1.741

MFCD00396380

4-{[(1,3-Benzothiazol-2-ylsulfanyl)acetyl]amino}benzoic acid

4-(2-(BENZOTHIAZOL-2-YLSULFANYL)-ACETYLAMINO)-BENZOIC ACID

Benzoic acid, 4-[[2-(2-benzothiazolylthio)acetyl]amino]-

PTP1B-IN-22

Use of PTP1B-IN-22

Names

PTP1B-IN-22 Biological Activity

Chemical & Physical Properties

Synonyms