TRAF6 Peptide trifluoroacetate salt

Modify Date: 2024-01-10 13:14:55

TRAF6 Peptide trifluoroacetate salt Structure
TRAF6 Peptide trifluoroacetate salt structure
Common Name TRAF6 Peptide trifluoroacetate salt
CAS Number 852805-92-6 Molecular Weight 3161.643
Density 1.3±0.1 g/cm3 Boiling Point 2698.5±65.0 °C at 760 mmHg
Molecular Formula C145H238N34O44 Melting Point N/A
MSDS N/A Flash Point 1585.8±34.3 °C

 Use of TRAF6 Peptide trifluoroacetate salt


TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].

 Names

Name TRAF6 Peptide trifluoroacetate salt
Synonym More Synonyms

 TRAF6 Peptide trifluoroacetate salt Biological Activity

Description TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
Related Catalog
In Vitro TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1]. TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1]. Western Blot Analysis[1] Cell Line: PC12 cells Concentration: 150 µM Incubation Time: 5 h Result: Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.
References

[1]. Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 2698.5±65.0 °C at 760 mmHg
Molecular Formula C145H238N34O44
Molecular Weight 3161.643
Flash Point 1585.8±34.3 °C
Exact Mass 3159.743164
LogP 5.04
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.556

 Synonyms

L-Lysine, L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-α-glutamyl-L-seryl-L-alanyl-L-serylglycyl- L-prolyl-L-seryl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-seryl-L-valyl-L-asparaginyl-L-phenylalanyl-L-leucyl-
L-Alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-α-glutamyl-L-seryl-L-alanyl-L-serylglycyl-L-prolyl-L -seryl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-seryl-L-valyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-lysine