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125720-21-0

125720-21-0 structure
125720-21-0 structure
  • Name: Fibronectin Adhesion-Promoting Peptide trifluoroacetate salt
  • Chemical Name: fibronectin adhesion-promoting peptide
  • CAS Number: 125720-21-0
  • Molecular Formula: C47H74N16O10
  • Molecular Weight: 1023.19000
  • Catalog: Peptides
  • Create Date: 2017-08-02 22:55:25
  • Modify Date: 2024-01-06 16:06:41
  • Heparin Binding Peptide is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.

Name fibronectin adhesion-promoting peptide
Synonyms trp-gln-pro-pro-arg-ala-arg-ile
h-trp-gln-pro-pro-arg-ala-arg-ile-oh
heparin-binding peptide
wqpprari
Description Heparin Binding Peptide is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.
Related Catalog
In Vitro GRGDS and Heparin Binding Peptide (WQPPRARI peptide) micropatterns increase the endothelialisation of prosthetic materials in vitro. WQPPRARI peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif[1]. RDGS and WQPPRARI peptides promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts[2].
References

[1]. Hoesli CA, et al. A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces. Biomaterials. 2014 Jan;35(3):879-90.

[2]. Chollet C, et al. Impact of peptide micropatterning on endothelial cell actin remodeling for cell alignment under shear stress. Macromol Biosci. 2012 Dec;12(12):1648-59.

Molecular Formula C47H74N16O10
Molecular Weight 1023.19000
Exact Mass 1022.58000
PSA 432.12000
LogP 2.99910
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport