Fibronectin Adhesion-Promoting Peptide trifluoroacetate salt

Modify Date: 2024-01-06 16:06:41

Fibronectin Adhesion-Promoting Peptide trifluoroacetate salt structure	Common Name	Fibronectin Adhesion-Promoting Peptide trifluoroacetate salt
	CAS Number	125720-21-0	Molecular Weight	1023.19000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₇H₇₄N₁₆O₁₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Fibronectin Adhesion-Promoting Peptide trifluoroacetate salt

Heparin Binding Peptide is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.

Name	fibronectin adhesion-promoting peptide
Synonym	More Synonyms

Description	Heparin Binding Peptide is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.
Related Catalog	Signaling Pathways >> Others >> Others Peptides Research Areas >> Cardiovascular Disease
In Vitro	GRGDS and Heparin Binding Peptide (WQPPRARI peptide) micropatterns increase the endothelialisation of prosthetic materials in vitro. WQPPRARI peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif[1]. RDGS and WQPPRARI peptides promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts[2].
References	[1]. Hoesli CA, et al. A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces. Biomaterials. 2014 Jan;35(3):879-90. [2]. Chollet C, et al. Impact of peptide micropatterning on endothelial cell actin remodeling for cell alignment under shear stress. Macromol Biosci. 2012 Dec;12(12):1648-59.

Molecular Formula	C₄₇H₇₄N₁₆O₁₀
Molecular Weight	1023.19000
Exact Mass	1022.58000
PSA	432.12000
LogP	2.99910

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

A synthetic peptide from the COOH-terminal heparin-binding domain of fibronectin promotes focal adhesion formation.

Mol. Biol. Cell 4 , 605, (1993)

Cell adhesion to extracellular matrix molecules such as fibronectin involves complex transmembrane signaling processes. Attachment and spreading of primary fibroblasts can be promoted by interactions ...

trp-gln-pro-pro-arg-ala-arg-ile

h-trp-gln-pro-pro-arg-ala-arg-ile-oh

heparin-binding peptide

wqpprari