LY 541850
Modify Date: 2025-08-25 18:17:44
LY 541850 structure
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Common Name | LY 541850 | ||
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| CAS Number | 852679-76-6 | Molecular Weight | 199.20 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H13NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LY 541850LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells. LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively[1]. |
| Name | LY 541850 |
|---|
| Description | LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells. LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively[1]. |
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| Related Catalog | |
| Target |
mGluR2:0.161 μM (IC50) mGluR3:1.05 μM (IC50) |
| In Vivo | LY 541850 (intraperitoneal injection; 10 mg/kg-300 mg/kg; 15 min prior) induces a concentration-dependent inhibition of the TAP evoked fEPSPs in CA1-SLM in 10-16 week old (EC50 42 nM) in CD-1 mice[1]. LY 541850 (intraperitoneal injection; 10 mg/kg-300 mg/kg; 30 min prior) reduces the increased locomotor activity of phencyclidine and amphetamine in a dose-dependent manner in male ICR mice[1]. |
| References |
| Molecular Formula | C9H13NO4 |
|---|---|
| Molecular Weight | 199.20 |