ARP 101

Modify Date: 2024-01-12 17:10:55

ARP 101 Structure
ARP 101 structure
Common Name ARP 101
CAS Number 849773-63-3 Molecular Weight 406.49600
Density N/A Boiling Point N/A
Molecular Formula C20H26N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARP 101


ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].

 Names

Name Butanamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-, (2R)
Synonym More Synonyms

 ARP 101 Biological Activity

Description ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].
Related Catalog
References

[1]. Jo YK, et al. ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. Biochem Biophys Res Commun. 2011;404(4):1039-1043.

 Chemical & Physical Properties

Molecular Formula C20H26N2O5S
Molecular Weight 406.49600
Exact Mass 406.15600
PSA 104.32000
LogP 4.68600
InChIKey DGZZVIWCMGVHGV-IBGZPJMESA-N
SMILES CC(C)ON(C(C(=O)NO)C(C)C)S(=O)(=O)c1ccc(-c2ccccc2)cc1

 Synonyms

arp 101
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