Fructose 2,6-biphosphate sodium salt

Modify Date: 2024-01-03 12:21:24

Fructose 2,6-biphosphate sodium salt structure	Common Name	Fructose 2,6-biphosphate sodium salt
	CAS Number	84364-89-6	Molecular Weight	362.098
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₁₄O₁₂P_2.xNa	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fructose 2,6-biphosphate sodium salt

Fructose 2,6-biphosphate sodium salt is a potent stimulator of 6-Phosphofructo-1-kinase (PFK-1) and also inhibits Fructose-1,6-Bisphosphatase[1].

Name	D-Fructose 2,6-diphosphate sodium salt
Synonym	More Synonyms

Description	Fructose 2,6-biphosphate sodium salt is a potent stimulator of 6-Phosphofructo-1-kinase (PFK-1) and also inhibits Fructose-1,6-Bisphosphatase[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	PFK-1, Fructose-1,6-Bisphosphatase[1]
In Vitro	A concentration-dependent inhibition of fructose-1,6-Bisphosphatase by Fructose 2,6-bisphosphate is observed. Another characteristic of this inhibition is that it changes the saturation curve from hyperbolic to sigmoidal. This effect is clearly apparent at 25 pM Fructose 2,6-bisphosphate. It appears that the inhibitory actions of Fructose 2,6-bisphosphate and of AMP are synergistic. Indeed, at 10 pM fructose 1,6-bisphosphate, the addition of AMP alone causes a 35% inhibition but, it increases the inhibition by 1 pM Fructose 2,6-bisphosphate from 20% to 80%[1].
References	[1]. Van Schaftingen E, et al. Inhibition of fructose-1,6-bisphosphatase by fructose 2,6-biphosphate. Proc Natl Acad Sci U S A. 1981 May;78(5):2861-3.

Risk Phrases	23/24/25-36/37/38-39/23/24/25
Safety Phrases	26-36/37-45

Sodium 2-O-(hydroxyphosphinato)-6-O-phosphono-β-D-fructofuranose

D-(-)-fructose

D-Arabino-hexulose

D-Fructose 2,6-bisphosphate sodium salt

β-D-Fructofuranose, 2,6-bis(dihydrogen phosphate), sodium salt (1:1)

D-fructofuranose

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