FA-Phe-Phe-OH

Modify Date: 2024-01-09 20:51:08

FA-Phe-Phe-OH structure	Common Name	FA-Phe-Phe-OH
	CAS Number	83661-95-4	Molecular Weight	432.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₄N₂O₅	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of FA-Phe-Phe-OH

FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

Name	N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanyl-L-phenylalanine
Synonym	More Synonyms

Description	FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
References	[1]. Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9. [2]. Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.

Description

FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

References

[1]. Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9.

[2]. Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.