83661-95-4

83661-95-4 structure

Name: FA-Phe-Phe-OH
Chemical Name: N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanyl-L-phenylalanine
CAS Number: 83661-95-4
Molecular Formula: C₂₅H₂₄N₂O₅
Molecular Weight: 432.47
Catalog: Signaling Pathways Metabolic Enzyme/Protease Angiotensin-converting Enzyme (ACE)
Create Date: 2016-02-21 08:41:28
Modify Date: 2024-01-09 20:51:08
FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

Name	N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanyl-L-phenylalanine
Synonyms	N-(3-(2-furyl)acryloyl)phenylalanine 3-(2-FURYL)ACRYLOYL-L-PHENYLALANINE 3-(2-furyl)acryloylglycyl-L-phenylalanine-L-phenylalanine N-<3-(2-furyl)acryloyl>-Phe-Phe FA-PHENYLALANINE Fua-Phe-Phe-OH N-<3-(2-furyl)acryloyl>-Phe Fua-Phe-Phe N-[3-(2-FURYL)ACRYLOYL]-L-PHENYLALANINE N-<3-<2>Furyl-acryloyl>-L-phenylalanin FA-Phe-Phe-OH

Description	FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
References	[1]. Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9. [2]. Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

63-91-2

71067-15-7

83661-95-4

26390-02-3

~56%

71115-83-8

83661-95-4

71115-83-8

83661-95-4

Precursor 3
63-91-2 26390-02-3 71115-83-8
DownStream 0