CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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AH2900000
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CHEMICAL NAME :
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Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester
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CAS REGISTRY NUMBER :
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82-98-4
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BEILSTEIN REFERENCE NO. :
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0031110
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C21-H25-N-O2
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MOLECULAR WEIGHT :
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323.47
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WISWESSER LINE NOTATION :
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T6NTJ A2 COVYR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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100 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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75 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intradermal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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150 mg/kg
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TOXIC EFFECTS :
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Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 59,149,1938
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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16 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
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