Diphenylacetyl chloride

Modify Date: 2024-01-02 19:15:39

Diphenylacetyl chloride Structure
Diphenylacetyl chloride structure
Common Name Diphenylacetyl chloride
CAS Number 1871-76-7 Molecular Weight 230.689
Density 1.2±0.1 g/cm3 Boiling Point 304.9±0.0 °C at 760 mmHg
Molecular Formula C14H11ClO Melting Point 49-53 °C(lit.)
MSDS Chinese USA Flash Point 154.9±18.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 2,2-diphenylacetyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 304.9±0.0 °C at 760 mmHg
Melting Point 49-53 °C(lit.)
Molecular Formula C14H11ClO
Molecular Weight 230.689
Flash Point 154.9±18.0 °C
Exact Mass 230.049850
PSA 17.07000
LogP 3.96
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.584

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AO6750000
CHEMICAL NAME :
Acetyl chloride, diphenyl-
CAS REGISTRY NUMBER :
1871-76-7
BEILSTEIN REFERENCE NO. :
1211588
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H11-Cl-O
MOLECULAR WEIGHT :
230.70
WISWESSER LINE NOTATION :
GVYR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6330 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4700 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37980 mg/kg/26W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H314-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R34;R36/37
Safety Phrases S26-S27-S28-S36/37/39-S45
RIDADR UN 3261 8/PG 2
WGK Germany 2
RTECS AO6750000
Packaging Group II
Hazard Class 8
HS Code 29163900

 Synthetic Route

 Customs

HS Code 29163900

 Articles2

More Articles
Selective pivaloylation and diphenylacetylation of cyclomalto-oligosaccharides.

Carbohydr. Res. 262(2) , 271-82, (1994)

Regioselective acylation of cyclomalto-oligosaccharides was achieved using pivaloyl and diphenylacetyl chlorides. The reaction of cyclomaltohexaose (1) with pivaloyl chloride gave the hexakis(2,6-di-O...

Synthesis and pharmacological screening of certain N-substituted amides structurally related to some local anesthetics.

Pharmazie 34(1) , 12-3, (1979)

Diphenylacetyl chloride and pivaloyl chloride have been condensed with a wide variety of amines. Some of the resulting amides showed local anesthetic properties higher than those of procaine hydrochlo...

 Synonyms

2,2-di(phenyl)acetyl chloride
2,2-di(phenyl)ethanoyl chloride
Diphenylacetyl chloride
Diphenylacetic acid chloride
EINECS 217-493-5
2,2-diphenylacetyl chloride
α,α-Diphenylacetyl chloride
Acetyl chloride,diphenyl
1,1-diphenylacetyl chloride
MFCD00013655
Benzeneacetyl chloride, α-phenyl-
2,2-diphenylethanoyl chloride