Benzilic acid

Modify Date: 2024-01-07 19:19:21

Benzilic acid Structure
Benzilic acid structure
Common Name Benzilic acid
CAS Number 76-93-7 Molecular Weight 228.243
Density 1.3±0.1 g/cm3 Boiling Point 409.0±40.0 °C at 760 mmHg
Molecular Formula C14H12O3 Melting Point 149-151 °C(lit.)
MSDS Chinese USA Flash Point 215.3±23.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name benzilic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 409.0±40.0 °C at 760 mmHg
Melting Point 149-151 °C(lit.)
Molecular Formula C14H12O3
Molecular Weight 228.243
Flash Point 215.3±23.8 °C
Exact Mass 228.078644
PSA 57.53000
LogP 3.03
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.623
Stability Stable. Incompatible with strong oxidizing agents. Combustible.
Water Solubility 1.41 g/L (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD2064000
CHEMICAL NAME :
Benzilic acid
CAS REGISTRY NUMBER :
76-93-7
BEILSTEIN REFERENCE NO. :
0521402
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H12-O3
MOLECULAR WEIGHT :
228.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S36-S36/37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DD2064000
HS Code 29181980

 Synthetic Route

 Customs

HS Code 29181980

 Articles1

More Articles
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.

Bioorg. Med. Chem. 17 , 5219-28, (2009)

In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop ...

 Synonyms

2-hydroxy-2,2-diphenylacetic acid
Benzylic acid
EINECS 200-993-2
Benzeneacetic acid, α-hydroxy-α-phenyl-
Benzilic acid
2-hydroxy-2,2-diphenylethanoic acid
Diphenylhydroxyacetic acid
2,2-diphenyl-2-hydroxyethanoic acid
Diphenylglycolic acid
4-10-00-01256 (Beilstein Handbook Reference)
2,2-Diphenyl-2-hydroxyacetic acid
2,2-Diphenyl-2-hydroxy acetate
Hydroxy(diphenyl)acetic acid
Glycolic acid,diphenyl
MFCD00004447
a-Hydroxy-a-phenylbenzeneacetic Acid
α-Hydroxy-2,2-diphenylacetic acid