Pharmazie 1979-01-01

Synthesis and pharmacological screening of certain N-substituted amides structurally related to some local anesthetics.

F El-Zahraa, S El-Basil, M El-Sayed, K M Ghoneim, M Khalifa

Index: Pharmazie 34(1) , 12-3, (1979)

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Abstract

Diphenylacetyl chloride and pivaloyl chloride have been condensed with a wide variety of amines. Some of the resulting amides showed local anesthetic properties higher than those of procaine hydrochloride.