1,2-Distearoyl-sn-glycero-3-phosphocholine
1,2-Distearoyl-sn-glycero-3-phosphocholine structure
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Common Name | 1,2-Distearoyl-sn-glycero-3-phosphocholine | ||
|---|---|---|---|---|
| CAS Number | 816-94-4 | Molecular Weight | 790.145 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H88NO8P | Melting Point | 236 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of 1,2-Distearoyl-sn-glycero-3-phosphocholine1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2]. |
| Name | 1,2-distearoyl-sn-glycero-3-phosphocholine |
|---|---|
| Synonym | More Synonyms |
| Description | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | In empty lipid nanoparticle (LNP) systems that do not contain siRNA, DSPC-cholesterol resides in outer layers, whereas in loaded systems a portion of the DSPC-cholesterol is internalised together with siRNA[2]. |
| References |
| Melting Point | 236 °C |
|---|---|
| Molecular Formula | C44H88NO8P |
| Molecular Weight | 790.145 |
| Exact Mass | 789.624756 |
| PSA | 121.00000 |
| LogP | 13.00 |
| InChIKey | NRJAVPSFFCBXDT-HUESYALOSA-N |
| SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| Precursor 10 | |
|---|---|
| DownStream 2 | |
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Exp. Parasitol. 146 , 78-86, (2014) Development of new generation of vaccines against leishmaniasis requires adjuvants to elicit the type and intensity of immune response needed for protection. The coupling of target-specific antibodies... |
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| EINECS 212-440-2 |
| MFCD00036905 |
| (2R)-2,3-Bis(stearoyloxy)propyl 2-(trimethylammonio)ethyl phosphate |
| 1,2-Distearoyl-sn-glycero-3-phosphocholine |
| Ethanaminium, 2-[[[(2R)-2,3-bis[(1-oxooctadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt |
| (2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate |
| L-α-PHOSPHATIDYLCHOLINE, DISTEAROYL |
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- Shanghai Nianxing Industrial Co., Ltd
- China
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- China
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- China
- Product Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
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- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 1,2-distearoyl-sn-glycero-3-phosphocholine
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