p32 inhibitor M36

Modify Date: 2025-08-25 00:12:41

p32 inhibitor M36 Structure
p32 inhibitor M36 structure
Common Name p32 inhibitor M36
CAS Number 802555-85-7 Molecular Weight 448.52
Density N/A Boiling Point N/A
Molecular Formula C23H28N8O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of p32 inhibitor M36


p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].

 Names

Name p32 Inhibitor M36

 p32 inhibitor M36 Biological Activity

Description p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].
Related Catalog
Target

p32[1]

In Vitro p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1]. p32 Inhibitor M36 is selective for p32 overexpressing cells[1]. p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].
References

[1]. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.

 Chemical & Physical Properties

Molecular Formula C23H28N8O2
Molecular Weight 448.52
InChIKey HHFOXYBNULCICF-UHFFFAOYSA-N
SMILES O=C(NCCCNC(=O)Nc1cccc(C2=NCCN2)c1)Nc1cccc(C2=NCCN2)c1
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