Tiglic acid

Modify Date: 2025-08-25 18:54:24

Tiglic acid structure	Common Name	Tiglic acid
	CAS Number	80-59-1	Molecular Weight	100.116
	Density	1.0±0.1 g/cm3	Boiling Point	198.5±0.0 °C at 760 mmHg
	Molecular Formula	C₅H₈O₂	Melting Point	61-64 °C(lit.)
	MSDS	Chinese USA	Flash Point	95.9±9.6 °C
	Symbol	GHS05	Signal Word	Danger

Use of Tiglic acid

Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite[1].

Name	tiglic acid
Synonym	More Synonyms

Description	Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. ROBERT E. BUCKLES, et al. THE PREPARATION OF TIGLIC AND ANGELIC ACIDS AND ESTERS. Cite This:J. Org. Chem.1950153680-684.

Density	1.0±0.1 g/cm3
Boiling Point	198.5±0.0 °C at 760 mmHg
Melting Point	61-64 °C(lit.)
Molecular Formula	C₅H₈O₂
Molecular Weight	100.116
Flash Point	95.9±9.6 °C
Exact Mass	100.052429
PSA	37.30000
LogP	1.35
Vapour Pressure	0.2±0.7 mmHg at 25°C
Index of Refraction	1.451
Storage condition	Refrigerator (+4°C)
Water Solubility	SOLUBLE IN HOT WATER

Tiglic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GQ5430000

CHEMICAL NAME :: Crotonic acid, 2-methyl-, (E)-

CAS REGISTRY NUMBER :: 80-59-1

BEILSTEIN REFERENCE NO. :: 1236500

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H8-O2

MOLECULAR WEIGHT :: 100.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36/37/39-S45-S24/25
RIDADR	UN 3261 8/PG 2
WGK Germany	2
RTECS	GQ5430000
Packaging Group	III
Hazard Class	8
HS Code	29161980

Precursor 7
CAS#:3017-71-8 2-bromo-2-butene CAS#:201230-82-2 carbon monoxide CAS#:30574-97-1 (E)-2-Methyl-2-... CAS#:3017-68-3 (z)-2-bromo-2-butene
CAS#:4403-61-6 2-METHYL-2-BUTE... CAS#:3586-58-1 Butanoic acid,2... CAS#:20068-02-4 (Z)-2-methyl-2-...
DownStream 10
CAS#:55449-44-0 methyl (R)-2-me... CAS#:10307-60-5 Methyl (2S)-2-m... CAS#:37526-88-8 benzyl tiglate CAS#:35660-94-7 trans-2-Methyl-...
CAS#:497-03-0 trans-2-Methyl-... CAS#:35842-45-6 N-TIGLOYLGLYCINE CAS#:14868-24-7 2,3-Dihydroxy-2... CAS#:212518-27-9 2-methyl-1-morp...
CAS#:193818-73-4 5-chloro-2-ethe... CAS#:78-59-1 Isophorone

HS Code	29161980

Largamides A-C, tiglic acid-containing cyclodepsipeptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confervoides.

Planta Med. 75 , 528-33, (2009)

Three unusual tiglic acid-containing cyclodepsipeptides, possessing the revised regioisomeric structures for largamides A-C (1-3), have been isolated from the marine cyanobacterium Lyngbya confervoide...

Pathway of formation of branched-chain volatile fatty acids in Ascaris mitochondria.

J. Parasitol. 67(6) , 841-6, (1981)

Disrupted Ascaris mitochondria formed 2-methylbutyrate (2-MB) and 2-methylvalerate (2-MV) when incubated anaerobically with acetyl CoA, propionyl CoA and NADH. However, when mitochondrial membranes we...

Biosynthesis of tiglic, ethacrylic, and 2-methylbutyric acids in a carabid beetle, Pterostichus (Hypherpes) californicus.

J. Chem. Ecol. 33(5) , 963-70, (2007)

Tiglic, 2-methylbutyric, and ethacrylic acids are found in the pygidial gland defensive fluid of many carabid beetles. By injecting a deuterium-labeled precursor into the carabid beetle Pterostichus (...

(2E)-2-Methyl-2-butenoic acid

2-Butenoic acid, 2-methyl-, (2E)-

FEMA 3599

2,3-Dimethylacrylic acid

EINECS 201-295-0

(2E)-2-Methylbut-2-enoic acid

Cevadic acid

Tiglic acid

E-Tiglic acid

MFCD00066864

Tiglate

(E)-2-methyl-2-butenoic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tiglic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Tiglic acid
Price: ￥98.0/20mg ￥318.0/100g ￥108.0/25g
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tiglic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Tiglic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Tiglic acid
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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