ENMD-1068 structure
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Common Name | ENMD-1068 | ||
|---|---|---|---|---|
| CAS Number | 789488-77-3 | Molecular Weight | 283.41000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H29N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ENMD-1068ENMD-1068 is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 can be used in the study of endometriosis and liver fibrosis[1][2]. |
| Name | 6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | ENMD-1068 is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 can be used in the study of endometriosis and liver fibrosis[1][2]. |
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| Related Catalog | |
| References |
| Molecular Formula | C15H29N3O2 |
|---|---|
| Molecular Weight | 283.41000 |
| Exact Mass | 283.22600 |
| PSA | 66.64000 |
| LogP | 1.79850 |
| InChIKey | VRZYMMVEALDDBH-UHFFFAOYSA-N |
| SMILES | CC(C)CC(=O)N1CCN(C(=O)CCCCCN)CC1 |
| Hazard Codes | Xn |
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| enmd-1068 |
| unii-stv44cbk1w |