1453868-32-0
1453868-32-0 structure
- Name: ENMD-2076 tartrate
- Chemical Name: ENMD-2076
- CAS Number: 1453868-32-0
- Molecular Formula: C25H31N7O6
- Molecular Weight: 525.557
- Create Date: 2020-01-19 21:40:55
- Modify Date: 2024-04-07 14:29:37
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A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2.
| Name | ENMD-2076 |
|---|---|
| Synonyms |
ENMD-2076
MFCD18074523 KXQ762CQTH (2R,3R)-2,3-Dihydroxysuccinic acid - 6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylvinyl]-4-pyrimidinamine (1:1) Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with 6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]-4-pyrimidinamine (1:1) MFCD18633211 |
| Description | A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2. |
|---|---|
| In Vitro | A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2; also inhibits Aurora B, c-Kit, FGFR1 (IC50=100-350 nM); orally bioactive.Liver CancerPhase 2 Clinical |
| Molecular Formula | C25H31N7O6 |
|---|---|
| Molecular Weight | 525.557 |
| Exact Mass | 525.233582 |