1-(2-(trimethylsilyl)ethoxycarbonyloxy)&

Modify Date: 2025-08-24 21:14:23

1-(2-(trimethylsilyl)ethoxycarbonyloxy)& Structure
1-(2-(trimethylsilyl)ethoxycarbonyloxy)& structure
Common Name 1-(2-(trimethylsilyl)ethoxycarbonyloxy)&
CAS Number 78269-85-9 Molecular Weight 259.331
Density 1.2±0.1 g/cm3 Boiling Point 308.6±44.0 °C at 760 mmHg
Molecular Formula C10H17NO5Si Melting Point 83-88ºC(lit.)
MSDS USA Flash Point 140.4±28.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 308.6±44.0 °C at 760 mmHg
Melting Point 83-88ºC(lit.)
Molecular Formula C10H17NO5Si
Molecular Weight 259.331
Flash Point 140.4±28.4 °C
Exact Mass 259.087585
PSA 72.91000
LogP 0.73
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.479
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2931900090

 Synthetic Route

~82%

1-(2-(trimethylsilyl)ethoxycarbonyloxy)& Structure

1-(2-(trimethyl...

CAS#:78269-85-9

Literature: GILEAD SCIENCES, INC. Patent: WO2008/11117 A2, 2008 ; Location in patent: Page/Page column 491 ; WO 2008/011117 A2

~79%

1-(2-(trimethylsilyl)ethoxycarbonyloxy)& Structure

1-(2-(trimethyl...

CAS#:78269-85-9

Literature: LEAD Therapeutics, Inc. Patent: US2010/105607 A1, 2010 ; US 20100105607 A1

~%

1-(2-(trimethylsilyl)ethoxycarbonyloxy)& Structure

1-(2-(trimethyl...

CAS#:78269-85-9

Literature: Synthesis, , # 4 p. 346 - 349

~%

1-(2-(trimethylsilyl)ethoxycarbonyloxy)& Structure

1-(2-(trimethyl...

CAS#:78269-85-9

Literature: Synthesis, , # 4 p. 346 - 349

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Synthesis and evaluation of novel activated mixed carbonate reagents for the introduction of the 2-(trimethylsilyl) ethoxycarbonyl (Teoc)-protecting group. Shute RE and Rich DH

Synthesis 1987(04 ) , 346-349, (1987)

 Synonyms

MFCD02683467
1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione
(2,5-dioxopyrrolidin-1-yl) 2-trimethylsilylethyl carbonate
2,5-Pyrrolidinedione, 1-[[[2-(trimethylsilyl)ethoxy]carbonyl]oxy]-
1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione
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