Br-PEG3-C2-Boc

Modify Date: 2024-01-10 12:11:48

Br-PEG3-C2-Boc Structure
Br-PEG3-C2-Boc structure
Common Name Br-PEG3-C2-Boc
CAS Number 782475-37-0 Molecular Weight 341.239
Density 1.2±0.1 g/cm3 Boiling Point 375.4±27.0 °C at 760 mmHg
Molecular Formula C13H25BrO5 Melting Point N/A
MSDS N/A Flash Point 180.8±23.7 °C

 Use of Br-PEG3-C2-Boc


Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 3-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}propanoate
Synonym More Synonyms

 Br-PEG3-C2-Boc Biological Activity

Description Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 375.4±27.0 °C at 760 mmHg
Molecular Formula C13H25BrO5
Molecular Weight 341.239
Flash Point 180.8±23.7 °C
Exact Mass 340.088531
LogP 1.68
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.464

 Safety Information

Hazard Codes Xi

 Synonyms

2-Methyl-2-propanyl 3-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}propanoate
Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
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