NSC 295642

Modify Date: 2024-01-09 19:29:29

NSC 295642 Structure
NSC 295642 structure
Common Name NSC 295642
CAS Number 77111-29-6 Molecular Weight 399.42100
Density N/A Boiling Point N/A
Molecular Formula C15H14ClCuN3S2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of NSC 295642


NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer[1].

 Names

Name (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane,chlorocopper(1+)

 NSC 295642 Biological Activity

Description NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer[1].
Related Catalog
In Vitro NSC 295642 (10 μM) 抑制 MKP-3 (PYST-1) 50% 或更多[1]。 NSC 295642 抑制 Cdc25A 的催化结构域[1]。 NSC 295642 对缺少调节 N 末端的截短形式的 Cdc25B 具有活性[1]。
References

[1]. Andreas Vogt, et al. Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol. 2003 Aug;10(8):733-42.  

 Chemical & Physical Properties

Molecular Formula C15H14ClCuN3S2
Molecular Weight 399.42100
Exact Mass 397.96100
PSA 62.91000
LogP 0.64340

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
RIDADR NONH for all modes of transport