NSC 295642

Names

[ Name ]:
NSC 295642

Biological Activity

[Description]:

NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Signaling Pathways >> Cell Cycle/DNA Damage >> PERK

[In Vitro]

NSC 295642 (10 μM) 抑制 MKP-3 (PYST-1) 50% 或更多[1]。 NSC 295642 抑制 Cdc25A 的催化结构域[1]。 NSC 295642 对缺少调节 N 末端的截短形式的 Cdc25B 具有活性[1]。

[References]

[1]. Andreas Vogt, et al. Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol. 2003 Aug;10(8):733-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₄ClCuN₃S₂

[ Molecular Weight ]:
399.42100

[ Exact Mass ]:
397.96100

[ PSA ]:
62.91000

[ LogP ]:
0.64340

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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