PF 356231
Modify Date: 2025-09-15 19:12:48
PF 356231 structure
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Common Name | PF 356231 | ||
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| CAS Number | 766536-21-4 | Molecular Weight | 428.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H20N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF 356231PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively[1]. |
| Name | (3R)-3-Phenyl-3-[({4-[4-(4-pyridinyl)phenyl]-2-thienyl}carbonyl)a mino]propanoic acid |
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| Description | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C25H20N2O3S |
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| Molecular Weight | 428.50 |
| Exact Mass | 428.11900 |
| PSA | 107.53000 |
| LogP | 5.81380 |
| InChIKey | VMTJQZUZINLEKC-JOCHJYFZSA-N |
| SMILES | O=C(O)CC(NC(=O)c1cc(-c2ccc(-c3ccncc3)cc2)cs1)c1ccccc1 |