Dynorphin A (1-8)

Modify Date: 2024-01-16 13:38:14

Dynorphin A (1-8) structure	Common Name	Dynorphin A (1-8)
	CAS Number	75790-53-3	Molecular Weight	981.15200
	Density	1.38g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₆H₇₂N₁₄O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dynorphin A (1-8)

Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].

Name	Dynorphin A (1-8), porcine,YGGFLRRI
Synonym	More Synonyms

Description	Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. Agbas A, Ahmed MS, Millington W, et al. Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry. Peptides. 1995;16(4):623-627. [2]. Ahmed MS, Zhou DH, Cavinato AG, Maulik D. Opioid binding properties of the purified kappa receptor from human placenta. Life Sci. 1989;44(13):861-871.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

References

[1]. Agbas A, Ahmed MS, Millington W, et al. Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry. Peptides. 1995;16(4):623-627.

[2]. Ahmed MS, Zhou DH, Cavinato AG, Maulik D. Opioid binding properties of the purified kappa receptor from human placenta. Life Sci. 1989;44(13):861-871.

Density	1.38g/cm3
Molecular Formula	C₄₆H₇₂N₁₄O₁₀
Molecular Weight	981.15200
Exact Mass	980.55600
PSA	411.05000
LogP	3.68290
Index of Refraction	1.637