75790-53-3

75790-53-3 structure

Name: Dynorphin A (1-8)
Chemical Name: Dynorphin A (1-8), porcine,YGGFLRRI
CAS Number: 75790-53-3
Molecular Formula: C₄₆H₇₂N₁₄O₁₀
Molecular Weight: 981.15200
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2018-05-12 08:00:00
Modify Date: 2024-01-16 13:38:14
Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].

Name	Dynorphin A (1-8), porcine,YGGFLRRI
Synonyms	dynorphin A fragment 1-8 DYNORPHIN A (1-8),PORCINE DYNORPHIN A PORCINE FRAGMENT 1-8 Ph-8p GFL PEPTIDE STANDARD dynorphin A (1-8) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH YGGFLRRI TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE dynorphin-(1-8)

Description	Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM)[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. Agbas A, Ahmed MS, Millington W, et al. Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry. Peptides. 1995;16(4):623-627. [2]. Ahmed MS, Zhou DH, Cavinato AG, Maulik D. Opioid binding properties of the purified kappa receptor from human placenta. Life Sci. 1989;44(13):861-871.

WGK Germany	3

75488-73-2

75790-53-3

83731-82-2

75790-53-3

83731-87-7

75790-53-3