N-Biotinyl-6-aminohexanoic acid

Modify Date: 2025-08-20 15:14:29

N-Biotinyl-6-aminohexanoic acid structure	Common Name	N-Biotinyl-6-aminohexanoic acid
	CAS Number	72040-64-3	Molecular Weight	357.46800
	Density	1.2g/cm3	Boiling Point	721.3ºC at 760 mmHg
	Molecular Formula	C₁₆H₂₇N₃O₄S	Melting Point	220-230ºC (dec.)
	MSDS	USA	Flash Point	390ºC

Use of N-Biotinyl-6-aminohexanoic acid

N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation[1].

Name	N-Biotinylcaproic Acid
Synonym	More Synonyms

Description	N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Synthesis of p-nitrophenyl N-acetyllactosaminide with β-D-galactosidase, chemical reduction of the p-nitrophenyl group, and sialylation with sialyltransferase. The p-aminophenyl glycosides are then successfully biotin-labeled through the coupling with N-(+)-biotinyl-6- aminohexanoic acid to afford biotinylated oligosaccharides with an aminohexanosyl group and phenyl group as the spacers between the biotin and glycan[1]. The SERS (surface-enhanced Raman scattering) of cyclohexyl isocyanide that silver nanoparticles modified with N-(+)-biotinyl-6-aminocaproic acid and cyclohexyl isocyanide can be anchored on a separate biotinylated substrate via the avidin-biotin interaction[2].
References	[1]. Zeng X, et al. Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and analysis of their interactions with lectins. Carbohydr Res. 2007 Jul 2;342(9):1244-8. [2]. Kim K, et al. microAg particle-based molecular sensing/recognition via surface-enhanced Raman spectroscopy. Biosens Bioelectron. 2007 Jan 15;22(6):1000-5.

Density	1.2g/cm3
Boiling Point	721.3ºC at 760 mmHg
Melting Point	220-230ºC (dec.)
Molecular Formula	C₁₆H₂₇N₃O₄S
Molecular Weight	357.46800
Flash Point	390ºC
Exact Mass	357.17200
PSA	132.83000
LogP	2.52190
Index of Refraction	1.532

N-Biotinyl-6-aminohexanoic acid MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	F: Flammable;
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport

D-Biotin

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6-Aminocaproic acid

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~76%

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Literature: Skander, Myriem; Humbert, Nicolas; Collot, Jerome; Gradinaru, Julieta; Klein, Gerard; Loosli, Andreas; Sauser, Jerome; Zocchi, Andrea; Gilardoni, Francois; Ward, Thomas R. Journal of the American Chemical Society, 2004 , vol. 126, # 44 p. 14411 - 14418

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6-Aminocaproic acid

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~79%

N-Biotinyl-6-am...

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cyanomethyl bio...

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N-Biotinyl-6-am...

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Literature: US2012/232262 A1, ; Page/Page column 3 ;

D-Biotin

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N-Biotinyl-6-am...

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Literature: US2012/232262 A1, ;

Biotin-PFP ester

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Methyl 6-aminoh...

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Precursor 5
CAS#:58-85-5 D-Biotin CAS#:60-32-2 6-Aminocaproic acid CAS#:35013-72-0 Biotin NHS CAS#:120550-35-8 Biotin-PFP ester
CAS#:1926-80-3 Methyl 6-aminoh...
DownStream 2
CAS#:89889-51-0 Biotin-C5-amino... CAS#:72040-63-2 Biotin-C5-NHS Ester

In vivo labeling of Escherichia coli cell envelope proteins with N-hydroxysuccinimide esters of biotin. Bradburne JA, Godfrey P, et al.

Appl. Environ. Microbiol. 59 , 663-668, (2993)

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Mol. Pharmacol. 68 , 1623-35, (2005)

The CB1 cannabinoid receptor has been shown to play important physiological roles in the central nervous system, as well as peripherally, and is a target for development of therapeutic medications. To...

microAg particle-based molecular sensing/recognition via surface-enhanced Raman spectroscopy.

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In this study, we demonstrate that powders of commercially available 2-microm-sized Ag (microAg) can be used as a core material for constructing molecular sensing/recognition units operating via surfa...

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