N4-ETHYL-2'-DEOXYCYTIDINE

Modify Date: 2024-01-10 17:28:14

N4-ETHYL-2'-DEOXYCYTIDINE structure	Common Name	N4-ETHYL-2'-DEOXYCYTIDINE
	CAS Number	70465-61-1	Molecular Weight	255.27
	Density	1.49 g/cm3	Boiling Point	466.7ºC at 760 mmHg
	Molecular Formula	C₁₁H₁₇N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	236.1ºC

Use of N4-ETHYL-2'-DEOXYCYTIDINE

N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	4-(ethylamino)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym	More Synonyms

Description	N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.49 g/cm3
Boiling Point	466.7ºC at 760 mmHg
Molecular Formula	C₁₁H₁₇N₃O₄
Molecular Weight	255.27
Flash Point	236.1ºC
Exact Mass	255.12200
PSA	96.61000

N4-Acetyl-2'-de...

CAS#:32909-05-0

~81%

N4-ETHYL-2'-DEO...

CAS#:70465-61-1

Literature: Sergueeva, Zinaida A.; Sergueev, Dmitri S.; Shaw, Barbara Ramsay Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 1-2 p. 275 - 282

3',5'-bis-O-ace...

CAS#:103931-23-3

Ethylamine

CAS#:75-04-7

~91%

N4-ETHYL-2'-DEO...

CAS#:70465-61-1

Literature: Kraszewski; Delort; Teoule Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864

3',5'-bis-O-ace...

CAS#:103931-23-3

Diethylamine

CAS#:109-89-7

~23%

N/A

CAS#:103931-27-7

N4-ETHYL-2'-DEO...

CAS#:70465-61-1

Literature: Kraszewski; Delort; Teoule Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864

3',5'-bis-O-ace...

CAS#:103931-23-3

N4-ETHYL-2'-DEO...

CAS#:70465-61-1

Literature: Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780

Precursor 4
CAS#:32909-05-0 N4-Acetyl-2'-de... CAS#:103931-23-3 3',5'-bis-O-ace... CAS#:75-04-7 Ethylamine CAS#:109-89-7 Diethylamine
DownStream 1
CAS#:195535-75-2 5'-O-DMT-N4-eth...