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N4-ETHYL-2'-DEOXYCYTIDINE

Names

[ CAS No. ]:
70465-61-1

[ Name ]:
N4-ETHYL-2'-DEOXYCYTIDINE

[Synonym ]:
2'-deoxy-N4-ethyl-cytidine
Cytidine,2'-deoxy-N-ethyl
N4-Ethyldeoxycytidin
N4-ethyl-2'-deoxy-cytidine

Biological Activity

[Description]:

N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.49 g/cm3

[ Boiling Point ]:
466.7ºC at 760 mmHg

[ Molecular Formula ]:
C11H17N3O4

[ Molecular Weight ]:
255.27

[ Flash Point ]:
236.1ºC

[ Exact Mass ]:
255.12200

[ PSA ]:
96.61000

Synthetic Route

Precursor & DownStream


Related Compounds