N4-Acetyl-2'-deoxycytidine

Names

[ Name ]:
N4-Acetyl-2'-deoxycytidine

[Synonym ]:
N-(1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
Cytidine, N-acetyl-2'-deoxy-
N4-Acetyl-2'-deoxycytidine
N-Acetyl-2'-deoxycytidine
N4-Acetyldeoxycytidine
N4-Acetyl-2-Deoxycytidine

Biological Activity

[Description]:

N-Acetyl-2′-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Melting Point ]:
154-161°C

[ Molecular Formula ]:
C₁₁H₁₅N₃O₅

[ Molecular Weight ]:
269.25

[ Exact Mass ]:
269.101166

[ PSA ]:
113.68000

[ LogP ]:
-1.05

[ Index of Refraction ]:
1.672

[ Storage condition ]:
Store at 0°C

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

N4-Acetyl-2'-deoxycytidine

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Precursor & DownStream

Precursor

DownStream

Related Compounds