N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine

Names

[ Name ]:
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine

[Synonym ]:
dmt-nac-dc
n-acetyl-5'-dmt deoxycytidine

Biological Activity

[Description]:

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.32±0.1 g/cm3(Predicted)

[ Molecular Formula ]:
C₃₂H₃₃N₃O₇

[ Molecular Weight ]:
571.62

[ Exact Mass ]:
587.22700

[ PSA ]:
141.37000

[ LogP ]:
2.91980

Synthetic Route

Click to get detail synthetic route

Related Compounds

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