Synthesis and cytostatic evaluation of 4-N-alkanoyl and 4-N-alkyl gemcitabine analogues

J Pulido, AJ Sobczak, J Balzarini…

Index: Kraszewski; Delort; Teoule Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864

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Citation Number: 6

Abstract

... Volume: Page: ... and its cellular uptake is primarily facilitated by human equilibrative nucleoside transport protein 1 (hENT1).(7) Gemcitabine is ... 4-amino group targeting extracellular DNA has been reported with low toxicity but high tumor efficacy.(27) In addition ...