Avobenzone

Modify Date: 2024-01-02 11:48:41

Avobenzone Structure
Avobenzone structure
Common Name Avobenzone
CAS Number 70356-09-1 Molecular Weight 310.387
Density 1.1±0.1 g/cm3 Boiling Point 463.6±35.0 °C at 760 mmHg
Molecular Formula C20H22O3 Melting Point 81-84 °C
MSDS Chinese USA Flash Point 203.1±26.0 °C
Symbol GHS09
GHS09
Signal Word Warning

 Use of Avobenzone


Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.Target: OthersAvobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. It can degrade faster in light in combination with mineral UV absorbers like zinc oxide and titanium dioxide, though with the right coating of the mineral particles this reaction can be reduced. A manganese doped titanium dioxide may be better than undoped titanium dioxide to improve avobenzone's stability. It reacts with minerals to form colored complexes. Manufacturers of avobenzone, like DSM recommend to include a chelator to prevent this from happening. They also recommend to avoid the inclusion of iron and ferric salts, heavy metals, formaldehyde donors and PABA and PABA esters[1].

 Names

Name 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)-1,3-propanedione
Synonym More Synonyms

 Avobenzone Biological Activity

Description Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.Target: OthersAvobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. It can degrade faster in light in combination with mineral UV absorbers like zinc oxide and titanium dioxide, though with the right coating of the mineral particles this reaction can be reduced. A manganese doped titanium dioxide may be better than undoped titanium dioxide to improve avobenzone's stability. It reacts with minerals to form colored complexes. Manufacturers of avobenzone, like DSM recommend to include a chelator to prevent this from happening. They also recommend to avoid the inclusion of iron and ferric salts, heavy metals, formaldehyde donors and PABA and PABA esters[1].
Related Catalog
References

[1]. Singh, P. and O.H. Nautiyal, Synthesis of Parsol [4-(1, 1-Dimethylethyl)-4'-methoxydibenzoylmethane)]. Asian Journal of Research in Chemistry, 2011. 4(11).

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 463.6±35.0 °C at 760 mmHg
Melting Point 81-84 °C
Molecular Formula C20H22O3
Molecular Weight 310.387
Flash Point 203.1±26.0 °C
Exact Mass 310.156891
PSA 43.37000
LogP 4.81
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.545

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P501
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes N
Risk Phrases R50/53
Safety Phrases S60-S61
RIDADR UN3077 9/PG 3
HS Code 29145000

 Synthetic Route

~96%

Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: DSM IP ASSETS B.V.; WEHRLI, Christof Patent: WO2012/84770 A1, 2012 ; Location in patent: Page/Page column 8-9 ;

~93%

Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: DSM IP ASSETS B.V.; WEHRLI, Christof Patent: WO2012/84770 A1, 2012 ; Location in patent: Page/Page column 10-11 ;

~%

Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: US2013/58879 A1, ; Paragraph 0194 ;

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Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: Journal de Chimie Physique et de Physico-Chimie Biologique, , vol. 95, # 2 p. 388 - 394

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Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: Journal of Photochemistry and Photobiology A: Chemistry, , vol. 209, # 2-3 p. 153 - 157

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Avobenzone Structure

Avobenzone

CAS#:70356-09-1

Literature: RSC Advances, , vol. 3, # 43 p. 19785 - 19788

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles29

More Articles
Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).

Anal. Chim. Acta 851 , 1-13, (2014)

This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrin...

Drug-excipient compatibility studies in binary mixtures of avobenzone.

J. Cosmet. Sci. 64(5) , 317-28, (2013)

During preformulation studies of cosmetic/pharmaceutical products, thermal analysis techniques are very useful to detect physical or chemical incompatibilities between the active and the excipients of...

Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.

Toxicol. Appl. Pharmacol. 283(2) , 147-55, (2015)

Allergic contact dermatitis (ACD) is a cell-mediated immune response that involves skin sensitization in response to contact with various allergens. Angiogenesis and lymphangiogenesis both play roles ...

 Synonyms

1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione
MFCD00210252
1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione
1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-
4-tert-Butyl-4'-methoxydibenzoylmethane
Avobenzone
1-(4-Methoxyphenyl)-3-[4-(2-methyl-2-propanyl)phenyl]-1,3-propanedione
1X1&1&R DV1VR DO1
EINECS 274-581-6
Avobenzone (USP)
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