γ-Caprolactone

Modify Date: 2025-08-21 15:06:41

γ-Caprolactone structure	Common Name	γ-Caprolactone
	CAS Number	695-06-7	Molecular Weight	114.142
	Density	1.0±0.1 g/cm3	Boiling Point	214.9±8.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₀O₂	Melting Point	-18°C
	MSDS	Chinese USA	Flash Point	98.3±0.0 °C
	Symbol	GHS07	Signal Word	Warning

Use of γ-Caprolactone

γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone can induce DNA damage, acts a substrate of Paraoxonase 1 (PON1)[1][2][3].

Name	γ-caprolactone
Synonym	More Synonyms

Description	γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone can induce DNA damage, acts a substrate of Paraoxonase 1 (PON1)[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel). 2018 Mar 2;18(3). [2]. Bianchi T, et al. Investigation of the aroma of commercial peach (Prunus persica L. Batsch) types by Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and sensory analysis. Food Res Int. 2017 Sep;99(Pt 1):133-146. [3]. Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019 Jul;93(7):2035-2043.

Description

γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone can induce DNA damage, acts a substrate of Paraoxonase 1 (PON1)[1][2][3].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel). 2018 Mar 2;18(3).

[2]. Bianchi T, et al. Investigation of the aroma of commercial peach (Prunus persica L. Batsch) types by Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and sensory analysis. Food Res Int. 2017 Sep;99(Pt 1):133-146.

[3]. Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019 Jul;93(7):2035-2043.

Density	1.0±0.1 g/cm3
Boiling Point	214.9±8.0 °C at 760 mmHg
Melting Point	-18°C
Molecular Formula	C₆H₁₀O₂
Molecular Weight	114.142
Flash Point	98.3±0.0 °C
Exact Mass	114.068077
PSA	26.30000
LogP	0.26
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.432

γ-Caprolactone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU4220000

CHEMICAL NAME :: 2(3H)-Furanone, 5-ethyldihydro-

CAS REGISTRY NUMBER :: 695-06-7

BEILSTEIN REFERENCE NO. :: 0107260

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H10-O2

MOLECULAR WEIGHT :: 114.16

WISWESSER LINE NOTATION :: T5OVTJ E2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,791,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,794,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,794,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6862 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	LU4220000
HS Code	2932209090

Precursor 8
CAS#:19781-77-2 6-HEPTEN-3-OL CAS#:108-94-1 Cyclohexanone CAS#:51827-43-1 4-hydroxyhexane... CAS#:1577-18-0 (E)-3-hexenoic acid
CAS#:628-02-4 n-Hexanamide CAS#:2407-43-4 2-hexen-4-olide CAS#:142-62-1 1-Hexanoic acid CAS#:4219-24-3 3-hexenoic acid
DownStream 10
CAS#:201991-50-6 5-ethylthiolan-2-one CAS#:109-67-1 Pent-1-ene CAS#:64-19-7 acetic acid CAS#:303752-16-1 1-cyclopentyl-7...
CAS#:6338-41-6 5-Hydroxymethyl... CAS#:3238-40-2 2,5-Furandicarb... CAS#:1117-74-4 4-OXO-HEXANOIC ACID CAS#:38401-84-2 2-Ethyl-1,6-dio...
CAS#:1120-73-6 2-methylcyclope... CAS#:13532-38-2 4-hydroxyhexano...

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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4-Hexanolide

γ-Ethyl-γ-butyrolactone

gamma-Hexanolactone

5-Ethyldihydrofuran-2(3H)-one

gamma-caprolactone

5-Ethyldihydrofuran-2(3H)-on

2(3H)-Furanone, 5-ethyldihydro-

5-Ethyldihydro-2(3H)-furanone

MFCD00005401

g-Caprolactone

EINECS 211-778-8

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: γ-Caprolactone
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: γ-Caprolactone
Price: ￥98.0/25g ￥298.0/100g
Purity: 99.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: gamma-Caprolactone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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γ-Caprolactone

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