2-Hydroxy-4-methoxybenzaldehyde

Modify Date: 2024-01-02 18:09:22

2-Hydroxy-4-methoxybenzaldehyde Structure
2-Hydroxy-4-methoxybenzaldehyde structure
Common Name 2-Hydroxy-4-methoxybenzaldehyde
CAS Number 673-22-3 Molecular Weight 152.15
Density 1.2±0.1 g/cm3 Boiling Point 271.5±20.0 °C at 760 mmHg
Molecular Formula C8H8O3 Melting Point 41-43 °C(lit.)
MSDS Chinese USA Flash Point 112.1±15.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Hydroxy-4-methoxybenzaldehyde


2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2].

 Names

Name 2-Hydroxy-4-methoxybenzaldehyde
Synonym More Synonyms

 2-Hydroxy-4-methoxybenzaldehyde Biological Activity

Description 2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2].
Related Catalog
Target

Tyrosinase[2].

References

[1]. Bodwell Graham, et al. An Inverse Electron-Demand Diels-Alder-Based Total Synthesis of Urolithin M7. Synlett. 2011 (15): 2245.

[2]. Kubo I, et al. 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants. Planta Med. 1999 Feb;65(1):19-22.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 271.5±20.0 °C at 760 mmHg
Melting Point 41-43 °C(lit.)
Molecular Formula C8H8O3
Molecular Weight 152.15
Flash Point 112.1±15.3 °C
Exact Mass 152.047348
PSA 46.53000
LogP 1.79
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.588

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ2810000
CHEMICAL NAME :
p-Anisaldehyde, 2-hydroxy-
CAS REGISTRY NUMBER :
673-22-3
BEILSTEIN REFERENCE NO. :
1072443
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
500 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BZ2810000
HS Code 29124900

 Synthetic Route

 Customs

HS Code 2912499000
Summary 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles15

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 Synonyms

o-Hydroxy-p-methoxybenzaldehyde
VHR BQ DO1
2-HO-4-MeO-C6H3CHO
2-Hydroxy-4-methoxybenzaldehyde
4-Methoxysalicylaldehyde
4-Methoxysalicyaldehyde
Salicylaldehyde, 4-methoxy-
Benzaldehyde,2-hydroxy-4-methoxy
2-Hydroxy-p-anisaldehyde
Benzaldehyde, 2-hydroxy-4-methoxy-
p-Anisaldehyde,2-hydroxy
2-hydroxy-4-methoxy benzaldehyde
4-methoxy-salicylaldehyde
Salicylaldehyde,4-methoxy
EINECS 211-604-0
4-methoxy-2-hydroxybenzaldehyde
MFCD00003327
p-Anisaldehyde, 2-hydroxy-
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