Tunicamycin V
Modify Date: 2024-01-10 17:41:30
Tunicamycin V structure
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Common Name | Tunicamycin V | ||
|---|---|---|---|---|
| CAS Number | 66054-36-2 | Molecular Weight | 830.91600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H62N4O16 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tunicamycin VTunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties[1][2]. |
| Name | tunicamycin A |
|---|---|
| Synonym | More Synonyms |
| Description | Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties[1][2]. |
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| Related Catalog | |
| Target |
IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))[1] |
| In Vitro | Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER)[2]. |
| References |
[2]. Kazuki Yamamoto, et al. Total Synthesis of Tunicamycin V. Org Lett. 2018 Jan 5;20(1):256-259. |
| Molecular Formula | C38H62N4O16 |
|---|---|
| Molecular Weight | 830.91600 |
| Exact Mass | 830.41600 |
| PSA | 311.82000 |
| (+)-tunicamycin V |
| tunicamycin B |
| tunicamycin V |
| tunicamycin-V |
| tunicamycin |