β-Rubromycin

Modify Date: 2024-01-03 15:31:49

β-Rubromycin Structure
β-Rubromycin structure
Common Name β-Rubromycin
CAS Number 27267-70-5 Molecular Weight 536.44000
Density 1.67g/cm3 Boiling Point 874.8ºC at 760mmHg
Molecular Formula C27H20O12 Melting Point N/A
MSDS N/A Flash Point 298.9ºC

 Use of β-Rubromycin


β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase). β-Rubromycin is a class of quinone antibacterials[1].

 Names

Name methyl (2S)-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate
Synonym More Synonyms

 β-Rubromycin Biological Activity

Description β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase). β-Rubromycin is a class of quinone antibacterials[1].
Related Catalog
Target

reverse transcriptase[1]

References

[1]. Goldman ME, et al. Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site. Mol Pharmacol. 1990;38(1):20-25.

 Chemical & Physical Properties

Density 1.67g/cm3
Boiling Point 874.8ºC at 760mmHg
Molecular Formula C27H20O12
Molecular Weight 536.44000
Flash Point 298.9ºC
Exact Mass 536.09500
PSA 168.03000
LogP 2.78290
Vapour Pressure 2.92E-32mmHg at 25°C
Index of Refraction 1.715

 Synonyms

tunicamycin VIII
TUNICAMYCIN C2 HOMOLOG