27267-70-5

27267-70-5 structure

Name: β-Rubromycin
Chemical Name: methyl (2S)-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate
CAS Number: 27267-70-5
Molecular Formula: C₂₇H₂₀O₁₂
Molecular Weight: 536.44000
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2017-02-06 22:31:00
Modify Date: 2024-01-03 15:31:49
β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase). β-Rubromycin is a class of quinone antibacterials[1].

Name	methyl (2S)-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate
Synonyms	tunicamycin VIII TUNICAMYCIN C2 HOMOLOG

Description	β-Rubromycin is a potent and selective inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymeras (reverse transcriptase). β-Rubromycin is a class of quinone antibacterials[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Reverse Transcriptase
Target	reverse transcriptase[1]
References	[1]. Goldman ME, et al. Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site. Mol Pharmacol. 1990;38(1):20-25.