N-acetyl-L-methionine

Modify Date: 2025-08-24 13:22:29

N-acetyl-L-methionine Structure
N-acetyl-L-methionine structure
 Common Name N-acetyl-L-methionine
CAS Number 65-82-7 Molecular Weight 191.248
Density 1.2±0.1 g/cm3 Boiling Point 371.3±52.0 °C at 760 mmHg
Molecular Formula C7H13NO3S Melting Point 104-107ºC
MSDS Chinese Flash Point 178.3±30.7 °C

 Use of N-acetyl-L-methionine


N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development[1].

 Names

Name N-acetyl-L-methionine
Synonym More Synonyms

 N-acetyl-L-methionine Biological Activity

Description N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development[1].
Related Catalog
References

[1]. Ball RO, et al. The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J Nutr. 2006 Jun;136(6 Suppl):1682S-1693S.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 371.3±52.0 °C at 760 mmHg
Melting Point 104-107ºC
Molecular Formula C7H13NO3S
Molecular Weight 191.248
Flash Point 178.3±30.7 °C
Exact Mass 191.061615
PSA 91.70000
LogP 0.95
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.532

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PD0480000
CHEMICAL NAME :
Methionine, N-acetyl-
CAS REGISTRY NUMBER :
65-82-7
BEILSTEIN REFERENCE NO. :
1725552
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H13-N-O3-S
MOLECULAR WEIGHT :
191.27
WISWESSER LINE NOTATION :
1VMYVQ2S1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
435 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,262,1970

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS PD0480000
HS Code 29309070

 Customs

HS Code 29309070

 Articles25

More Articles
Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.

Anal. Biochem. 308 , 285-293, (2002)

The hydrolysis of N-acetyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by porcine kidney acylase I (EC 3.5.1.14) was monitored by the heat released upon ...

Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine.

Arch. Insect Biochem. Physiol. 38(1) , 44-52, (1998)

Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basi...

Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin.

J. Biol. Chem. 264(19) , 11491-6, (1989)

Genes for the various isoactins define two classes of actin. Class I actin genes code for Met-Asp(Glu)-actin, and class II actin genes code for Met-X-Asp(Glu)-actin where X is usually cysteine. Amino ...

 Synonyms

EINECS 200-617-7
MFCD00064441
N-Acetyl-L-methionine
N-acetyl-methionine
Thiomedon
L-Methionine, N-acetyl-
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
Acetylmethionine
Methionine, N-acetyl-, L-
Methionamine
L-N-Acetyl-Methionine
L-(N-Acetyl)methionine
Ac-Met-OH
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