O-Desmethyl Metoprolol

Modify Date: 2024-01-06 20:14:15

O-Desmethyl Metoprolol structure	Common Name	O-Desmethyl Metoprolol
	CAS Number	62572-94-5	Molecular Weight	253.33700
	Density	1.085g/cm3	Boiling Point	424.6ºC at 760 mmHg
	Molecular Formula	C₁₄H₂₃NO₃	Melting Point	70-72ºC
	MSDS	Chinese USA	Flash Point	210.6ºC
	Symbol	GHS07	Signal Word	Warning

Use of O-Desmethyl Metoprolol

O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol.

Name	O-Desmethyl Metoprolol
Synonym	More Synonyms

Density	1.085g/cm3
Boiling Point	424.6ºC at 760 mmHg
Melting Point	70-72ºC
Molecular Formula	C₁₄H₂₃NO₃
Molecular Weight	253.33700
Flash Point	210.6ºC
Exact Mass	253.16800
PSA	61.72000
LogP	1.35000
Index of Refraction	1.531

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA0512150

CHEMICAL NAME :: Benzeneethanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-

CAS REGISTRY NUMBER :: 62572-94-5

LAST UPDATED :: 198809

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H23-N-O3

MOLECULAR WEIGHT :: 253.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport
RTECS	DA0512150

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1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

O-Desmethyl Metoprolol

Use of O-Desmethyl Metoprolol

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Articles1

Synonyms